Types of PGT: PGT-A, PGT-M, PGT-SR Explained

Planning a pregnancy can be an exciting but sometimes overwhelming journey, especially for couples who are considering IVF. One of the tools that can make this journey more reassuring is Preimplantation Genetic Testing (PGT). 



This test helps identify genetic issues in embryos before pregnancy, giving couples more confidence about the chances of a healthy baby.

PGT isn’t just one test—it comes in different types, each designed to address specific concerns. Understanding the differences between PGT-A, PGT-M, and PGT-SR can help you make informed choices with your fertility specialist.

What Is Preimplantation Genetic Testing?

PGT is done during an IVF cycle. After eggs are fertilized in the lab, embryos are allowed to grow for a few days. At this stage, a small number of cells are carefully collected from each embryo and tested for genetic or chromosomal abnormalities.

This testing helps doctors select the healthiest embryos for implantation, improving the chances of a successful pregnancy and reducing the risk of miscarriage. Couples who have experienced repeated pregnancy loss or have known genetic conditions often consult an IVF Specialist in Noida to decide which type of PGT might be right for them.

PGT-A: Screening for Chromosomal Health

PGT-A, or Preimplantation Genetic Testing for Aneuploidy, is the most common type of PGT. It checks all 23 pairs of chromosomes in an embryo to detect any missing or extra chromosomes—conditions that can lead to failed implantation or miscarriage.

PGT-A is especially helpful for women of advanced maternal age or for couples who have experienced multiple IVF failures. By selecting embryos with the correct number of chromosomes, doctors can increase the likelihood of a healthy pregnancy. Couples undergoing IVF test tube baby treatment in Noida often choose PGT-A to maximize their chances of success.

PGT-M: Testing for Specific Genetic Disorders

PGT-M is designed for couples who are at risk of passing on a known genetic disorder. These single-gene conditions can include disorders like thalassemia, cystic fibrosis, or Huntington’s disease.

With PGT-M, embryos are tested to ensure they do not carry the harmful gene. Only embryos free of the specific genetic condition are considered for transfer. This type of testing offers peace of mind to families with a history of inherited disorders, helping them reduce the risk of passing the condition to their child.

PGT-SR: Detecting Structural Chromosomal Changes

PGT-SR is for detecting structural chromosomal abnormalities, such as translocations or inversions. These changes might not affect a parent’s health but can cause infertility, miscarriage, or developmental issues in children.

By identifying embryos with balanced chromosomes, PGT-SR allows doctors to select the embryos most likely to result in a healthy pregnancy. Couples with unexplained infertility or repeated IVF failures often benefit from this specialized testing.

How PGT Supports IVF Success

PGT adds an important layer of precision to the IVF process. Testing embryos before transfer helps:

  • Improve implantation success rates
  • Reduce the risk of miscarriage
  • Avoid passing on serious genetic disorders
  • Increase the chances of a healthy pregnancy

A well-equipped IVF Center in Noida ensures that PGT is performed safely and accurately. Your fertility specialist can guide you in choosing the right type of testing based on your personal medical history and reproductive goals.

Who Can Benefit from PGT?

PGT is often recommended for couples who have:

  • Experienced recurrent pregnancy loss
  • Known genetic conditions in the family
  • Multiple failed IVF attempts
  • Women of advanced maternal age

Couples in these situations can benefit from the additional information PGT provides, helping them make more informed choices and reducing the emotional and physical strain of repeated IVF cycles. A trusted Best Gynecologist in Noida or infertility specialist can help determine which type of PGT is best for you.

Final Thoughts

PGT-A, PGT-M, and PGT-SR each play a unique role in modern IVF. By testing embryos for chromosomal or genetic issues before pregnancy, these tests give couples the opportunity to make informed choices and improve the likelihood of a healthy pregnancy.

With guidance from an experienced Infertility Specialist in Noida and support from a reputable IVF center, couples can approach IVF with more confidence, clarity, and peace of mind.

 

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